The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7935347 B1

PDF
Full Text
Expired
Date of Patent:
May. 03, 2011

Filed:

Dec. 01, 2004
Applicants:

Andreas Nandy, Hamburg, DE;

Helmut Fiebig, Schwarzenbeck, DE;

Oliver Cromwell, Suesel-Fassendorf, DE;

Inventors:

Andreas Nandy, Hamburg, DE;

Helmut Fiebig, Schwarzenbeck, DE;

Oliver Cromwell, Suesel-Fassendorf, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/36 (2006.01); A01N 37/18 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to the preparation of DNA sequences of group 4 major allergens from cereals. The invention also includes fragments, novel combinations of partial sequences and point mutations with hypoallergenic effects. The recombinant DNA molecules and the derived polypeptides, fragments, novel combinations of partial sequences and variants can be used for therapy of pollen-allergy diseases. The proteins produced by recombination can be applied to in-vitro and in-vivo diagnosis of pollen allergies.


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