The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2011

Filed:

Apr. 14, 2006
Applicants:

W. Grant Mcgimpsey, Boylston, MA (US);

Christopher R. Lambert, Hudson, MA (US);

John S. Benco, Holliston, MA (US);

Venkat R. Thalladi, Worcester, MA (US);

Inventors:

W. Grant McGimpsey, Boylston, MA (US);

Christopher R. Lambert, Hudson, MA (US);

John S. Benco, Holliston, MA (US);

Venkat R. Thalladi, Worcester, MA (US);

Assignee:

Worcester Polytechnic Institute, Worcester, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/62 (2006.01); G01N 21/64 (2006.01); G01N 27/00 (2006.01); G01N 33/00 (2006.01); G01N 33/20 (2006.01); G01N 33/48 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/533 (2006.01);
U.S. Cl.
CPC ...
Abstract

In various aspects are provided a microfluidic and/or nanofluidic sensor that can provide an indication of the reliability of its measurement of the presence of an analyte in a sample under investigation, an analyte concentration in the sample under investigation, or both. The provided sensors, microfluidic devices, and methods of analyte detection, utilize two transduction mechanisms from the same molecule to determine analyte presence, analyte concentration, or both. An analyte sensing molecule is used that can provide both an optical signal and electrochemical signal when an analyte is recognized by an analyte binding portion of the sensing molecule.


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