The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Dec. 12, 2007
N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
Chester Chenguang Yuan, Newbury Park, CA (US);
Nianhe Han, Thousand Oaks, CA (US);
Qingyian Liu, Camarillo, CA (US);
Dustin Mcminn, Pacifica, CA (US);
Jay Powers, Pacifica, CA (US);
Chester Chenguang Yuan, Newbury Park, CA (US);
Nianhe Han, Thousand Oaks, CA (US);
Qingyian Liu, Camarillo, CA (US);
Dustin McMinn, Pacifica, CA (US);
Jay Powers, Pacifica, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention provides N-cyclohexyl benzamide and benzeneacetamide compounds according to formula (I): where R, R, R, R, R, R, R, R, R, R, R, R, R, m, n, p, and q are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of the compounds and compositions of the invention for the treatment of conditions associated with hydroxysteroid dehydrogenases (e.g., 11β-HSD1), and the use of the compounds of the invention in the preparation of medicaments for the treatment of hydroxysteroid dehydrogenase-associated conditions.