The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2011

Filed:

Dec. 16, 2005
Applicants:

Pavel Bobal, Malacky, SK;

Jaroslav Frantisek, Brno, CZ;

Jiri Stohandl, Bobrova, CZ;

Kane Denike, Georgetown, CA;

Armin Boerner, Rostock, DE;

Vitali Tararov, Moscow, RU;

Andrei Korostylev, Ryazan, RU;

Gerd Koenig, Zwickau, DE;

Nicolas Jeker, Dornach, CH;

Inventors:

Pavel Bobal, Malacky, SK;

Jaroslav Frantisek, Brno, CZ;

Jiri Stohandl, Bobrova, CZ;

Kane Denike, Georgetown, CA;

Armin Boerner, Rostock, DE;

Vitali Tararov, Moscow, RU;

Andrei Korostylev, Ryazan, RU;

Gerd Koenig, Zwickau, DE;

Nicolas Jeker, Dornach, CH;

Assignee:

ratiopharm GmbH, Ulm, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/33 (2006.01); C07D 207/335 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for preparing pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids from 1,4-diketo starting materials. The invention further relates to intermediates in this process formula (I).


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