The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Apr. 02, 2008
Paul John Beswick, Harlow, GB;
David Kenneth Dean, Harlow, GB;
Robert James Gleave, Harlow, GB;
Andrew Peter Moses, Harlow, GB;
Daryl Simon Walter, Harlow, GB;
Paul John Beswick, Harlow, GB;
David Kenneth Dean, Harlow, GB;
Robert James Gleave, Harlow, GB;
Andrew Peter Moses, Harlow, GB;
Daryl Simon Walter, Harlow, GB;
Glaxo Group Limited, Greenford, Middlesex, GB;
Abstract
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor (P2X7 receptor antagonists). The invention also provides the use of such compounds or salts, or pharmaceutical compositions thereof, in the treatment or prevention of disorders/diseases mediated by the P2X7 receptor, for example pain, inflammation or a neurodegenerative disease, in particular pain such as inflammatory pain, neuropathic pain or visceral pain.