The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Dec. 05, 2005
Bernardo Herradon García, Juan de la Cierva, ES;
Roberto Chicharro Martin, Juan de la Cierva, ES;
Vicente Jesús Aran Redo, Juan de la Cierva, ES;
Mercedes Alonso Giner, Juan de la Cierva, ES;
Bernardo Herradon García, Juan de la Cierva, ES;
Roberto Chicharro Martin, Juan de la Cierva, ES;
Vicente Jesús Aran Redo, Juan de la Cierva, ES;
Mercedes Alonso Giner, Juan de la Cierva, ES;
Consejo Superior de Investigaciones Cientificas, Madrid, ES;
Abstract
The invention relates to derivative compounds of partially-reduced isoquinoline with substitution of a sec-butyl group at position 3 with calpain inhibitor activity. The inventive compound comprises an ester or amide derived from (3-sec-butyl-1-oxo-2,3-dihydro-1H-isoquinolin-4-yliden)-acetic acid and (3-sec-butyl-1-thioxo-2, 3-dihydro-1H-isoquinolin-4-yliden)-acetic acid. Compounds having formula I or II can be used in the preventive or therapeutic treatment of a degenerative disease.