The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Dec. 15, 2006
Applicants:
Jie Wang, Englewood Cliffs, NJ (US);
Yi Pan, Jiansu, CN;
Assignee:
Naturemed Group Corporation, Englewood Cliffs, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 221/28 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the preparation and pharmacological use of sinomenine derivatives of formula I. The approach disclosed herein is the modification of D ring by-substituting for R. Additional substitutions in the other rings are also provided herein. Several of the sinomenine derivatives have significantly greater anti-inflammation activity when compared with the parent compound.