The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2011

Filed:

Apr. 05, 2007
Applicants:

Savithri Ramurthy, Walnut Creek, CA (US);

Xiaodong Lin, Walnut Creek, CA (US);

Sharadha Subramanian, San Ramon, CA (US);

Alice Rico, Castro Valley, CA (US);

Xiaojong M. Wang, Livermore, CA (US);

Rama Jain, Fremont, CA (US);

Jeremy M. Murray, Emeryville, CA (US);

Stephen E. Basham, Oakland, CA (US);

Robert L. Warne, San Leandro, CA (US);

Wei Shu, Danville, CA (US);

Yasheen Zhou, Moraga, CA (US);

Jeffrey Dove, Castro Valley, CA (US);

Mina Aikawa, Alameda, CA (US);

Payman Amiri, Walnut Creek, CA (US);

Weibo Wang, Moraga, CA (US);

Johanna M. Jansen, San Francisco, CA (US);

Allan S. Wagman, Belmont, CA (US);

Keith B. Pfister, San Ramon, CA (US);

Simon NG, Walnut Creek, CA (US);

Inventors:

Savithri Ramurthy, Walnut Creek, CA (US);

Xiaodong Lin, Walnut Creek, CA (US);

Sharadha Subramanian, San Ramon, CA (US);

Alice Rico, Castro Valley, CA (US);

Xiaojong M. Wang, Livermore, CA (US);

Rama Jain, Fremont, CA (US);

Jeremy M. Murray, Emeryville, CA (US);

Stephen E. Basham, Oakland, CA (US);

Robert L. Warne, San Leandro, CA (US);

Wei Shu, Danville, CA (US);

Yasheen Zhou, Moraga, CA (US);

Jeffrey Dove, Castro Valley, CA (US);

Mina Aikawa, Alameda, CA (US);

Payman Amiri, Walnut Creek, CA (US);

Weibo Wang, Moraga, CA (US);

Johanna M. Jansen, San Francisco, CA (US);

Allan S. Wagman, Belmont, CA (US);

Keith B. Pfister, San Ramon, CA (US);

Simon Ng, Walnut Creek, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.


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