The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Jun. 12, 2006
François Nantel, Sherbrooke, CA;
Roger Chammas, Sao Paulo SP, BR;
Pierre Sirois, Orford, CA;
Bruno Joseph Battistini, Orford, CA;
François Nantel, Sherbrooke, CA;
Roger Chammas, Sao Paulo SP, BR;
Pierre Sirois, Orford, CA;
Bruno Joseph Battistini, Orford, CA;
Abstract
Provided is a method for the use of a bradykinin B1 receptor antagonist of formula I: X-CO-Aaa-Aaa-Aaa-Aaa-Gly-α(Me)Phe-Ser-D-βNal-Aaa-OH (I) or a pharmaceutically acceptable salt or hydrate thereof wherein: X is CHor CH—CH, where n is an integer from 1 to 3, and i is an integer from 0 to 3; Aaais Lys, Orn or Cit; Aaais Arg or Cit, and preferably Arg; Aaais Oic, Hyp or Pro, and preferably Oic; Aaais Pro or Oic, and preferably Pro; and Aaais Ile, Leu or Nle, and preferably Ile, for the treatment of metastases, cancers and/or chemotherapy-induced neuropathies, comprising the administration of the compound to a patient in need of such treatment. Also provided are compositions containing such antagonists and their thereof.