The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Feb. 20, 2003
Seung Bum Park, Arlington, MA (US);
David Barnes-seeman, Cambridge, MA (US);
Angela N. Koehler, Cambridge, MA (US);
Stuart L. Schreiber, Boston, MA (US);
Seung Bum Park, Arlington, MA (US);
David Barnes-Seeman, Cambridge, MA (US);
Angela N. Koehler, Cambridge, MA (US);
Stuart L. Schreiber, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention provides compositions and methods to facilitate the identification of compounds that are capable of interacting with a biological macromolecule of interest. A composition is provided that comprises an array of chemical compounds attached to a solid support, wherein the density of the array of compounds is at least 1000 spots per cm. The inventive arrays are generated by: providing a solid support functionalized with a selected chemical moiety capable of interacting with a chemical compound to form an attachment and delivering compounds to the solid support having a density of at least 1000 spots per cm. The present invention also provides methods for utilizing these arrays to identify small molecule partners for biological macromolecules of interest.