The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2011
Filed:
Nov. 25, 2004
Kazuhiro Machida, Shizuoka, JP;
Takashi Nakashima, Kanagawa, JP;
Yasuhide Aritoku, Shizuoka, JP;
Toshio Tsuchida, Shizuoka, JP;
Kazuhiro Machida, Shizuoka, JP;
Takashi Nakashima, Kanagawa, JP;
Yasuhide Aritoku, Shizuoka, JP;
Toshio Tsuchida, Shizuoka, JP;
Mercian Corporation, Tokyo, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a DNA participating in biological transformation of a macrolide compound 11107B. The present invention provides, particularly, a DNA participating in biological transformation of a macrolide compound 11107B represented by the formula (I) into a 16-position hydroxy macrolide compound 11107D represented by the formula (II), the DNA encoding a protein having 16-position hydroxylating enzymatic activity or ferredoxin, to a method of isolating the DNA, to a protein encoded by the DNA, a plasmid carrying the DNA, a transformant obtained by transforming using the plasmid and a method of producing a 16-position hydroxy compound by using the transformant.