The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
Dec. 14, 2009
Philip Hass, Moss Beach, CA (US);
Jianping Yin, Foster City, CA (US);
Kenneth Katschke, Millbrae, CA (US);
Micah Steffek, Walnut Creek, CA (US);
Menno Van Lookeren Campagne, San Francisco, CA (US);
Christian Wiesmann, Brisbane, CA (US);
Philip Hass, Moss Beach, CA (US);
Jianping Yin, Foster City, CA (US);
Kenneth Katschke, Millbrae, CA (US);
Micah Steffek, Walnut Creek, CA (US);
Menno Van Lookeren Campagne, San Francisco, CA (US);
Christian Wiesmann, Brisbane, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
The present invention concerns determination of the crystal structure of the macrophage specific receptor, CRIg (earlier referred to as STIgMA), and its complex with the C3b and C3c subunits of complement C3 (C3b:CRIg and C3c:CRIg complexes). The invention further concerns the use of the crystal structure of CRIg or the C3b:CRIg complex to screen for and identify molecules structurally and/or functionally related to CRIg, including CRIg agonists and antagonists.