The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
May. 19, 2006
Yuichiro Tani, Edogawa-ku, JP;
Yutaka Kitagawa, Edogawa-ku, JP;
Makoto Muto, Edogawa-ku, JP;
Toshiaki Jyono, Edogawa-ku, JP;
Yuichiro Tani, Edogawa-ku, JP;
Yutaka Kitagawa, Edogawa-ku, JP;
Makoto Muto, Edogawa-ku, JP;
Toshiaki Jyono, Edogawa-ku, JP;
Daiichi Sankyo Company, Limited, Tokyo, JP;
Abstract
The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent. The invention provides a method for producing a compound represented by formula (2): (wherein n is an integer of 2 to 5; Rrepresents a (substituted) alkyl group or a (substituted) aryl group; and Rrepresents a (substituted) alkoxycarbonyl group, a (substituted) aralkyloxycarbonyl group, a (substituted) aliphatic acyl group, or a (substituted) aromatic acyl group), which includes treating a compound represented by formula (1): (wherein n, R, and Rare the same as defined above; and Rrepresents a hydrogen atom, a (substituted) alkyl group, or a (substituted) aralkyl group) under a hydrogen gas atmosphere in the presence of a metallic catalyst.