The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2011

Filed:

Mar. 03, 2008
Applicants:

Hartmuth C. Kolb, Playa Del Rey, CA (US);

Joseph C. Walsh, Pacific Palisades, CA (US);

Robert M Yeh, Culver City, CA (US);

Kai Chen, Los Angeles, CA (US);

Umesh Gangadharmath, Los Angeles, CA (US);

Brian Duclos, Los Angeles, CA (US);

Vani P. Mocharla, Los Angeles, CA (US);

Farhad Karimi, Canton, MA (US);

Henry C. Padgett, Hermosa Beach, CA (US);

Qianwa Liang, Hacienda Heights, CA (US);

Tieming Zhao, Los Angeles, CA (US);

Inventors:

Hartmuth C. Kolb, Playa Del Rey, CA (US);

Joseph C. Walsh, Pacific Palisades, CA (US);

Robert M Yeh, Culver City, CA (US);

Kai Chen, Los Angeles, CA (US);

Umesh Gangadharmath, Los Angeles, CA (US);

Brian Duclos, Los Angeles, CA (US);

Vani P. Mocharla, Los Angeles, CA (US);

Farhad Karimi, Canton, MA (US);

Henry C. Padgett, Hermosa Beach, CA (US);

Qianwa Liang, Hacienda Heights, CA (US);

Tieming Zhao, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein are novel radiolabeled nucleosides and methods for detecting cellular proliferation in a mammal, the method comprising administrating an effective amount of a radiolabeled nucleoside; the method comprising: a) administering to the mammal a diagnostically effective amount of the nucleoside to the mammal; b) allowing the nucleoside to distribute into the effective tissue; and c) imaging the tissue, wherein an increase in binding of the compound to tissue compared to a normal control level of binding indicates that the mammal is suffering from a disease involving cellular proliferation.


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