The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
Sep. 18, 2007
Applicants:
Brian K. Shoichet, San Francisco, CA (US);
Fabrio Prati, Reggio Emilia, IT;
Inventors:
Brian K. Shoichet, San Francisco, CA (US);
Fabrio Prati, Reggio Emilia, IT;
Assignees:
Northwestern University, Evanston, IL (US);
University of Modena, Reggio Emilia, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G61K 31/69 (2006.01); G61K 31/445 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C β-lactamase AmpC. The new compounds improve inhibition by over two-orders of magnitude compared to analogous glycylboronic acids, with Ki values as low as 1 nM.