The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
Aug. 05, 2008
Kyeong Kyu Kim, Gyeonggi-do, KR;
Sung Wook Kang, Gyeonggi-do, KR;
Kyeong Kyu Kim, Gyeonggi-do, KR;
Sung Wook Kang, Gyeonggi-do, KR;
Sungkyunkwan University Foundation for Corporate Collaboration, Suwon-si, Gyeonggi-do, KR;
Abstract
The present invention relates to a method for in vitro phosphorylation of TRAP derived from. In the present invention, the TRAP is first identified as a kinase that self-phosphorylates and is phosphorylated specifically in the presence of an oxidative metal ion such as iron, copper and zinc. Based upon this finding, a novel method for in vitro phosphorylation of purified TRAP is provided and also, a method for screening various chemicals and natural materials by using the above method is provided in order to select inhibitors against the TRAP phosphorylation. The inhibitors are expected to be applied for novel antibiotics of, because this TRAP phosphorylation is essential to infect. Therefore, the present invention can be widely used to develop novel drugs againstand their resistant strains, in near future.