The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
Sep. 29, 2004
Jay D. Keasling, Berkeley, CA (US);
Jack D. Newman, Berkeley, CA (US);
Douglas J. Pitera, Oakland, CA (US);
Sydnor T. Withers, Iii, Richmond, CA (US);
Keith Kinkead Reiling, San Francisco, CA (US);
Vincent J. J. Martin, Kensington, CA (US);
Jay D. Keasling, Berkeley, CA (US);
Jack D. Newman, Berkeley, CA (US);
Douglas J. Pitera, Oakland, CA (US);
Sydnor T. Withers, III, Richmond, CA (US);
Keith Kinkead Reiling, San Francisco, CA (US);
Vincent J. J. Martin, Kensington, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The present invention provides isolated, genetically modified host cells, where a host cell is genetically modified with a nucleic acid that includes a nucleotide sequence encoding a biosynthetic pathway enzyme. Synthesis of the enzyme in the host cell results in conversion of a substrate for the enzyme into a biosynthetic pathway intermediate, which intermediate is produced in an amount effective to inhibit growth of the genetically modified host cell. The present invention further provides compositions and kits comprising a subject genetically modified host cell. Subject host cells are useful for identifying a gene product having activity in a biosynthetic pathway. The present invention further provides methods of identifying a gene product having activity in a biosynthetic pathway.