The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2011

Filed:

Dec. 21, 2005
Applicants:

Arava Veera Reddy, Hyderabad, IN;

Siripalli Udaya Bhaskara Rao, Hyderabad, IN;

Chinnapillai Rajendiran, Hyderabad, IN;

Venkateswarlu Jasti, Hyderabad, IN;

Inventors:

Arava Veera Reddy, Hyderabad, IN;

Siripalli Udaya Bhaskara Rao, Hyderabad, IN;

Chinnapillai Rajendiran, Hyderabad, IN;

Venkateswarlu Jasti, Hyderabad, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/10 (2006.01); C07D 257/00 (2006.01); C07F 5/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to an improved process for the preparation of Losartan. The process comprising reacting 2-n-butyl-4-chloro-5-formyl imidazole with 2-(4-bromomethyl) benzonitrile in the presence of a phase transfer catalyst and an alkali, and reducing the resulting cyano aldehyde to produce a cyano alcohol which is further reacted with sodium azide in N-methyl pyrrolidinone and a salt to produce Losartan.


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