The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2011
Filed:
Nov. 29, 2007
Sabine Kolczewski, Loerrach, DE;
Claus Riemer, Freiburg, DE;
Lucinda Steward, Basel, CH;
Juergen Wichmann, Steinen, DE;
Thomas Woltering, Grenzach-Wyhlen, DE;
Sabine Kolczewski, Loerrach, DE;
Claus Riemer, Freiburg, DE;
Lucinda Steward, Basel, CH;
Juergen Wichmann, Steinen, DE;
Thomas Woltering, Grenzach-Wyhlen, DE;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The present invention relates to 2-Aminoquinoline derivatives of general formula I and pharmaceutically-acceptable acid-addition salts thereof, wherein R, Rand X are as defined in the specification. The compounds may be used as 5-HTreceptor antagonists. The present invention relates also to processes for making such a compound and a pharmaceutical composition comprising such a compound. Compounds of the present invention are useful in the prevention and/or treatment of anxiety depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, dementia, disorders of eating behaviors, sexual dysfunction, sleep disorders, withdrawal from abuse of drugs, motor disorders such as Parkinson's disease, psychiatric disorders and gastrointestinal disorders.