The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2011
Filed:
Dec. 22, 2008
Takehiro Ishikawa, Azumino, JP;
Hitoshi Inoue, Azumino, JP;
Satoko Kobayashi, Azumino, JP;
Masako Yoshida, Azumino, JP;
Hiroaki Shiohara, Azumino, JP;
Yasunori Ueno, Azumino, JP;
Nobuyuki Tanaka, Azumino, JP;
Takehiro Ishikawa, Azumino, JP;
Hitoshi Inoue, Azumino, JP;
Satoko Kobayashi, Azumino, JP;
Masako Yoshida, Azumino, JP;
Hiroaki Shiohara, Azumino, JP;
Yasunori Ueno, Azumino, JP;
Nobuyuki Tanaka, Azumino, JP;
Kissei Pharmaceutical Co., Ltd., Nagano, JP;
Abstract
The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein Rand Rare each hydrogen, lower acyl, lower alkoxycarbonyl or the like; Ris halo-lower alkyl, lower acyl, halo-lower alkylcarbonyl, cycloalkylcarbonyl, optionally substituted arylcarbonyl, lower alkoxycarbonyl or the like; Ris lower alkyl, halo-lower alkyl, cycloalkyl, lower alkoxy-lower alkyl or the like, which exhibit potent COMT inhibitory activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.