The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2011
Filed:
Sep. 23, 2009
Masakazu Ban, Osaka, JP;
Hiroshi Suhara, Osaka, JP;
Masato Horiuchi, Osaka, JP;
Noriyoshi Yamamoto, Osaka, JP;
Hiroshi Enomoto, Osaka, JP;
Hiroyuki Inoue, Osaka, JP;
Masakazu Ban, Osaka, JP;
Hiroshi Suhara, Osaka, JP;
Masato Horiuchi, Osaka, JP;
Noriyoshi Yamamoto, Osaka, JP;
Hiroshi Enomoto, Osaka, JP;
Hiroyuki Inoue, Osaka, JP;
Santen Pharmaceutical Co., Ltd., Osaka-shi, Osaka, JP;
Abstract
A compound having the following formula wherein A is —O—; B is alkylene or alkenylene optionally containing —O—, —S—, —(NR)—, —CO— or —N═; Rand Rare alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl is unsubstituted or substituted by halogen, cycloalkyl, aryl, adamantyl or amino; Ris a substituted or unsubstituted pyridine ring; Rand Rare hydrogen or alkyl; Ris hydrogen or alkyl; X is O or S; and each hydrogen of the said amino is unsubstituted or substituted by alkyl, alkoxycarbonyl, cycloalkyloxycarbonyl, arylalkoxycarbonyl or halogenoalkyloxycarbonyl. The compound is a TNF-α production inhibitor that is useful for treating autoimmune diseases such as rheumatoid arthritis.