The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2011
Filed:
Jun. 11, 2003
Evert Johannes Bunschoten, Heesch, NL;
Herman Jan Tijmen Coelingh Bennink, Driebergen, NL;
Christian Franz Holinka, New York, NY (US);
Evert Johannes Bunschoten, Heesch, NL;
Herman Jan Tijmen Coelingh Bennink, Driebergen, NL;
Christian Franz Holinka, New York, NY (US);
Pantarhei Bioscience B.V., , NL;
Abstract
A method of treating or preventing an immune mediated disorder in a mammal, said method comprising the administration of a therapeutically effective amount of an estrogenic component to said mammal, wherein the estrogenic component is selected from the group consisting of: substances represented by the following formula: in which formula R, R, R, Rindependently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R, R, Ris a hydroxyl group; no more than 3 of R, R, R, Rare hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors. Another aspect of the invention relates to a pharmaceutical formulation comprising the aforementioned estrogenic component, an immunotherapeutic agent and a pharmaceutically acceptable excipient.