The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
Sep. 24, 2004
Reiner Babiel, Seehausen, DE;
Norbert Franken, Starnberg, DE;
Hermann Leying, Bichl, DE;
Judith Pinsl-ober, Tutzing, DE;
Thomas Vess, El Sobrante, CA (US);
Guenter Ziegler, Polling, DE;
Reiner Babiel, Seehausen, DE;
Norbert Franken, Starnberg, DE;
Hermann Leying, Bichl, DE;
Judith Pinsl-Ober, Tutzing, DE;
Thomas Vess, El Sobrante, CA (US);
Guenter Ziegler, Polling, DE;
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Abstract
Method and apparatus, including computer program products, implement techniques for quantifying a target nucleic acid (target) in a test sample. The techniques include providing a target and a defined initial amount of an internal control nucleic acid (control) different from the target; amplifying the target and control in a common amplification process; measuring a quantity indicating the amount of amplification product for the target and for the control in relation to a parameter representing the progress of the amplification; determining a characteristic value of the progress parameter for the target based on measurement results related to the amount of target amplification product; possibly determining a characteristic value of the progress parameter for the control based on measurement results related to the amount of control amplification product; and quantifying the original amount of target according to a predefined or selected quantification scheme using at least the characteristic value for the target.