The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
Feb. 16, 2006
Takahiro Ishii, Tokyo, JP;
Takashi Sugane, Tokyo, JP;
Jun Maeda, Tokyo, JP;
Fumie Narazaki, Tokyo, JP;
Akio Kakefuda, Tokyo, JP;
Kentaro Sato, Tokyo, JP;
Tatsuhisa Takahashi, Tokyo, JP;
Takatoshi Kanayama, Tokyo, JP;
Chikashi Saitoh, Tokyo, JP;
Jotaro Suzuki, Tokyo, JP;
Chisato Kanai, Tokyo, JP;
Takahiro Ishii, Tokyo, JP;
Takashi Sugane, Tokyo, JP;
Jun Maeda, Tokyo, JP;
Fumie Narazaki, Tokyo, JP;
Akio Kakefuda, Tokyo, JP;
Kentaro Sato, Tokyo, JP;
Tatsuhisa Takahashi, Tokyo, JP;
Takatoshi Kanayama, Tokyo, JP;
Chikashi Saitoh, Tokyo, JP;
Jotaro Suzuki, Tokyo, JP;
Chisato Kanai, Tokyo, JP;
Astellas Pharma, Inc., Tokyo, JP;
Abstract
To provide a compound usable for treatment of diseases associated with fatty acid amide hydrolase (FAAH), especially for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain. We have found that a novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative of the present invention has an excellent effect for increasing an effective bladder capacity, an excellent effect for relieving urinary frequency and an excellent anti-allodynia effect, and is therefore usable for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.