The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2011

Filed:

Feb. 08, 2006
Applicants:

Rajender Kamboj, Burnaby, CA;

Michael D. Winther, Vancouver, CA;

Robert Fraser, Vancouver, CA;

Mikhail Chafeev, Burnaby, CA;

Sultan Chowdhury, Surrey, CA;

Jian-min Fu, Burnaby, CA;

Duanjie Hou, Burnaby, CA;

Shifeng Liu, Port Coquitlam, CA;

Vandna Raina, Vancouver, CA;

Mehran Seid Bagherzadeh, North Vancouver, CA;

Serguei Sviridov, Burnaby, CA;

Kashinath Sadalapure, Edmonton, CA;

Shaoyi Sun, Vancouver, CA;

Vishnumurthy Kodumuru, Burnaby, CA;

Nagasree Chakka, Burnaby, CA;

Zaihui Zhang, Vancouver, CA;

Melwyn Abreo, Jamul, CA;

Mikhail A. Kondratenko, San Diego, CA (US);

Daniel F. Harvey, San Diego, CA (US);

Cindy J. Hudson, Buena Park, CA (US);

Wenbao LI, San Diego, CA (US);

Chi Tu, San Diego, CA (US);

Sengen Sun, San Diego, CA (US);

Mark W. Holladay, San Diego, CA (US);

Heinz W. Gschwend, Santa Rosa, CA (US);

Inventors:

Rajender Kamboj, Burnaby, CA;

Michael D. Winther, Vancouver, CA;

Robert Fraser, Vancouver, CA;

Mikhail Chafeev, Burnaby, CA;

Sultan Chowdhury, Surrey, CA;

Jian-Min Fu, Burnaby, CA;

Duanjie Hou, Burnaby, CA;

Shifeng Liu, Port Coquitlam, CA;

Vandna Raina, Vancouver, CA;

Mehran Seid Bagherzadeh, North Vancouver, CA;

Serguei Sviridov, Burnaby, CA;

Kashinath Sadalapure, Edmonton, CA;

Shaoyi Sun, Vancouver, CA;

Vishnumurthy Kodumuru, Burnaby, CA;

Nagasree Chakka, Burnaby, CA;

Zaihui Zhang, Vancouver, CA;

Melwyn Abreo, Jamul, CA;

Mikhail A. Kondratenko, San Diego, CA (US);

Daniel F. Harvey, San Diego, CA (US);

Cindy J. Hudson, Buena Park, CA (US);

Wenbao Li, San Diego, CA (US);

Chi Tu, San Diego, CA (US);

Sengen Sun, San Diego, CA (US);

Mark W. Holladay, San Diego, CA (US);

Heinz W. Gschwend, Santa Rosa, CA (US);

Assignee:

Xenon Pharmaceuticals Inc., Burnaby, British Columbia, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); C07D 211/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention is directed to the use of SCD-1 inhibitors of the formula (I): where x, y, V, W, G, J, L, M, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein, in combination with other drug therapies to treat adverse weight gain.


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