The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2011

Filed:

Apr. 02, 2004
Applicants:

Ju-ock Nam, Daegu, KR;

Jung-eun Kim, Daegu, KR;

Ha-won Jeong, Daegu, KR;

Sung-jin Lee, Daegu, KR;

Byung-heon Lee, Daegu, KR;

Je-yong Choi, Daegu, KR;

Rang-woon Park, Daegu, KR;

Jae-yong Park, Daegu, KR;

In-san Kim, Daegu, KR;

Inventors:

Ju-Ock Nam, Daegu, KR;

Jung-Eun Kim, Daegu, KR;

Ha-Won Jeong, Daegu, KR;

Sung-Jin Lee, Daegu, KR;

Byung-Heon Lee, Daegu, KR;

Je-Yong Choi, Daegu, KR;

Rang-Woon Park, Daegu, KR;

Jae-Yong Park, Daegu, KR;

In-San Kim, Daegu, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the use of a peptide that interacts with the αvβ3 integrin of endothelial cells. More particularly, the invention relates to a method for inhibiting endothelial cell adhesion, endothelial cell migration and/or angiogenesis, using a peptide consisting of at least 18 amino acids, comprising tyrosine-histidine (TY) or asparagines-histidine (NH), and at least three hydrophobic amino acids with bulky side chains; or equivalents thereof. Furthermore, the invention provides a method for treating or preventing angiogenesis-related diseases, using the peptide.


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