The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
May. 30, 2007
Stephen Maxwell Taylor, Bellbird Park, AU;
Ian Alexander Shiels, Muirlea, AU;
Lindsay Charles Brown, Sinnamon Park, AU;
Michael Wellesley Whitehouse, Holland Park, AU;
Stephen Maxwell Taylor, Bellbird Park, AU;
Ian Alexander Shiels, Muirlea, AU;
Lindsay Charles Brown, Sinnamon Park, AU;
Michael Wellesley Whitehouse, Holland Park, AU;
Promics Pty Limited, Macquarie Park, New South Wales, AU;
Abstract
This invention relates to the use of an antagonist of a G protein-coupled receptor in the prevention and/or treatment of fibrosis, such as the treatment of fibrosis associated with myocardial infarction or diabetes or certain pulmonary conditions. In a preferred embodiment, the antagonist is a C5a receptor antagonist, more preferably a cyclic peptide antagonist of the C5a receptor. In particular, the invention provides a method of prevention, treatment or alleviation of a fibrotic condition, comprising the step of administering an effective amount of an antagonist of a G protein-coupled receptor to a subject in need of such treatment.