The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
Jan. 24, 2008
Ralph R. Weichselbaum, Chicago, IL (US);
Dennis E. Hallahan, Nashville, TN (US);
Donald W. Kufe, Wellesley, MA (US);
Vikas P. Sukhatme, Newton, MA (US);
Ralph R. Weichselbaum, Chicago, IL (US);
Dennis E. Hallahan, Nashville, TN (US);
Donald W. Kufe, Wellesley, MA (US);
Vikas P. Sukhatme, Newton, MA (US);
The University of Chicago, Chicago, IL (US);
Dana-Farber Cancer Institute, Boston, MA (US);
Abstract
The present disclosure demonstrates the successful use of constitutive promoters operatively linked to genes encoding radiosensitizing or radioprotecting factors, administered to cells, tissues, or patients in conjunction with radiation exposure. Also disclosed are pharmacological preparations to be used to increase the levels of radiosensitizing compounds such as TNF-α, or radioprotective compounds such as MnSOD, in specified tissues or tumors of a subject.