The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
Jun. 17, 2004
Timothy Charles Ramsey Prickett, Christchurch, NZ;
Eric Arnold Espiner, Madison, WI (US);
Arthur Mark Richards, Christchurch, NZ;
Timothy Grant Yandle, Christchurch, NZ;
Michael Gary Nicholls, Christchurch, NZ;
Timothy Charles Ramsey Prickett, Christchurch, NZ;
Eric Arnold Espiner, Madison, WI (US);
Arthur Mark Richards, Christchurch, NZ;
Timothy Grant Yandle, Christchurch, NZ;
Michael Gary Nicholls, Christchurch, NZ;
Otago Innovation Limited, Dunedin, NZ;
Abstract
A means of measuring and monitoring skeletal growth rate using a plasma analyte, amino-terminal C-type natriuretic peptide (NT-CNP). Plasma NT-CNP concentrations reflect the potential for further growth of the immature skeleton. Measurement of plasma NT-CNP in a subject, when related to the mean of an appropriate age and gender matched set of control subjects, provides an index of the severity of a growth disorder not otherwise available and facilitates diagnosis in children with undetected osteo-chondrodysplasias or other intrinsic disorders of the growth plate. The invention also provides a means of detecting and monitoring potentially harmful effects of drugs and other factors on skeletal growth long before they are evident using current methods in clinical practice.