The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
Jul. 29, 2004
Sylvain Fleury, Lausanne, CH;
Marc P Girard, Lyons, FR;
Marie-gaëlle Roger, Grenoble, FR;
Nicolas Mouz, Grenoble, FR;
Pierre-françois Serres, Saint-Genis Laval, FR;
Sylvain Fleury, Lausanne, CH;
Marc P Girard, Lyons, FR;
Marie-Gaëlle Roger, Grenoble, FR;
Nicolas Mouz, Grenoble, FR;
Pierre-François Serres, Saint-Genis Laval, FR;
Mymetics Corporation, New York, NY (US);
Abstract
The present invention concerns a modified polypeptide containing at least an immunodominant region and the connecting loop between N- and C-helices of gp41 ectodomain of HIV-1, wherein the connecting loop includes at least a linker fragment having: —a size convenient for keeping the native conformation of the interaction between N- and C-helices, and —an hydrophily sufficient to provide a soluble and stable trimeric form to said modified polypeptide.