The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2011

Filed:

Aug. 19, 2005
Applicants:

Stanley P. Pensak, Jr., East Walpole, MA (US);

John Heden, Hollis, NH (US);

Steven J. Ciavarini, Natick, MA (US);

John Lamoureux, Franklin, MA (US);

Miguel Soares, Norton, MA (US);

Inventors:

Stanley P. Pensak, Jr., East Walpole, MA (US);

John Heden, Hollis, NH (US);

Steven J. Ciavarini, Natick, MA (US);

John Lamoureux, Franklin, MA (US);

Miguel Soares, Norton, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G05D 11/02 (2006.01); G05D 11/16 (2006.01); G05B 21/00 (2006.01); G01F 1/00 (2006.01); G01F 7/00 (2006.01); G01F 25/00 (2006.01); F01N 3/20 (2006.01); G05B 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream to enhance chromatographic performance related to retention time and reproducibility. The injection event is coordinated with active pressure control of a binary solvent delivery system to virtually eliminate the customary pressure drop when the low-pressure loop is brought on line. Consistent timing with the injection event of the mechanical position of the delivery pump pistons, and the start and subsequent gradient delivery generates reproducible results.


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