The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Dec. 21, 2005
Arava Veera Reddy, Hyderabad, IN;
Siripalli Udaya Bhaskara Rao, Hyderabad, IN;
Chinnapillai Rajendiran, Hyderabad, IN;
Venkateswarlu Jasti, Hyderabad, IN;
Arava Veera Reddy, Hyderabad, IN;
Siripalli Udaya Bhaskara Rao, Hyderabad, IN;
Chinnapillai Rajendiran, Hyderabad, IN;
Venkateswarlu Jasti, Hyderabad, IN;
Suven Life Sciences Limited, Hyderabad, IN;
Abstract
The invention relates to a improved process for the preparation of Losartan and its potassium salt, which comprises: (i) reacting bromo OTBN with BCFI in the presence of a base and a phase transfer catalyst to produce a cyano aldehyde; reacting the formed cyano aldehyde with sodium azide in the presence of tributyl tin chloride to produce aldehyde tetrazole; reducing the formed aldehyde tetrazole with sodium borohydride to produce Losartan; and, if desired, converting the formed Losartan to its potassium salt by known method.