The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2011

Filed:

Aug. 11, 2008
Applicants:

Scott J. Hultgren, St. Louis, MO (US);

Jerome S. Pinkner, St. Louis, MO (US);

Fredrik Almqvist, Umea, SE;

Nils Pemberton, Umea, SE;

Veronica Aberg, Umea, SE;

Andreas Larsson, Umea, SE;

Inventors:

Scott J. Hultgren, St. Louis, MO (US);

Jerome S. Pinkner, St. Louis, MO (US);

Fredrik Almqvist, Umea, SE;

Nils Pemberton, Umea, SE;

Veronica Aberg, Umea, SE;

Andreas Larsson, Umea, SE;

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 279/00 (2006.01); C07F 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel amino methylated 2-pyridinones, precursors, intermediates, and derivatives; the methods for the preparation of the same; uses of the same for inhibiting pili formation in bacteria; and pharmaceutical compositions comprising these compounds are described in this application. The present compounds may be employed to inhibit biofilm formation and thereby inhibit adherence of bacteria to a host cell.


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