The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Dec. 30, 2004
Christian Sund, Huddinge, SE;
Nathalie Roue, Huddinge, SE;
Stefan Lindstrom, Huddinge, SE;
Dmitry Antonov, Huddinge, SE;
Christer Sahlberg, Huddinge, SE;
Katarina Jansson, Huddinge, SE;
Christian Sund, Huddinge, SE;
Nathalie Roue, Huddinge, SE;
Stefan Lindstrom, Huddinge, SE;
Dmitry Antonov, Huddinge, SE;
Christer Sahlberg, Huddinge, SE;
Katarina Jansson, Huddinge, SE;
Medivir AB, Huddinge, SE;
Abstract
Compounds of the formula Z: where; A is CH or N; Ris a substituent to a carbon atom in the ring containing A selected from —S(═O)Ra, where Ra is —C-Calkyl, —ORx, —NRxRx, —NHNRxRx, —NHNHC(═O)ORx, —NRxOH; —C(═O)—Rb, where Rb is —CT-C4-alkyl, ORx, —NRxRx, —NHNRxRx, —NHC-C-alkyl-C(═O)Orx —NRxRc, where Rc is H, C-Calkyl, —NRxRx; —C(=0)Rd, —CN, S(═O)pRx, where Rd is Rd is C1-C4-alkyl, —ORx, —NRxRx C-C-alkyl-O—C1-C3-alkylC(═O)ORx, —C-C-alkyl-COORx; —C-Calkyl-OH or C-Calkyl ethers or esters thereof (O—C-Calkyl)q-O—Rx a 5 or 6 membered aromatic ring having 1-3 hetero atoms p is 1 or 2; Rx is independently selected from H, C-Calkyl or acetyl; or a pair of Rx can together with the adjacent N atom form a ring; L is -0-, —S(═O)—, or —CH—, where r is 0, 1 or 2; R-Rare substituents as defined in the specification; X is —(CRR')n-D-(CRR′)m-; D is a bond, —NR—, -0-, —S—, —S(=0)- or —S(=0)-; and pharmaceutically acceptable salts and prodrugs thereof, have utility as HIV antivirals.