The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 2011

Filed:

Aug. 03, 2005
Applicants:

Sherman T. Waddell, Westfield, NJ (US);

James M. Balkovec, Martinsville, NJ (US);

Gina M. Santorelli, Oceanport, NJ (US);

Aaron H. Leeman, Portland, ME (US);

Milana Maletic, Summit, NJ (US);

Xin Gu, Scotch Plains, NJ (US);

Inventors:

Sherman T. Waddell, Westfield, NJ (US);

James M. Balkovec, Martinsville, NJ (US);

Gina M. Santorelli, Oceanport, NJ (US);

Aaron H. Leeman, Portland, ME (US);

Milana Maletic, Summit, NJ (US);

Xin Gu, Scotch Plains, NJ (US);

Assignee:

Merck Sharp & Dohme, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/166 (2006.01); A61K 31/403 (2006.01); A61P 3/00 (2006.01); C07C 235/70 (2006.01); C07D 223/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Sulfonyl derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome or Syndrome X, and other symptoms associated with NIDDM.


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