The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Oct. 08, 2004
Andrzej Kutner, Warsaw, PL;
Jacek Martynow, Warsaw, PL;
Michal Chodynski, Pruszkow, PL;
Wieslaw Szelejewski, Warsaw, PL;
Hanna Fitek, Warsaw, PL;
Malgorzata Krupa, Warsaw, PL;
Andrzej Kutner, Warsaw, PL;
Jacek Martynow, Warsaw, PL;
Michal Chodynski, Pruszkow, PL;
Wieslaw Szelejewski, Warsaw, PL;
Hanna Fitek, Warsaw, PL;
Malgorzata Krupa, Warsaw, PL;
Instytut Farmaceutyczny, Warsaw, PL;
Abstract
Disclosed is a process for the preparation of 24-alkyl analogs of cholecalcyferol of Formula 1 having a (5E) or (5Z) configuration, wherein X represents a hydrogen atom, a hydroxy group or an ORgroup, where R, Rand Rmay be the same or different and represent groups suitable for hydroxyl protection, and Ris a Calkyl chain or a Ccykloalkyl group, optionally substituted with Calkyl groups, especially for calcipotriol. The invention also provides new intermediates and non-racemic compounds being valuable synthones for the synthesis of pharmacologically active substances.