The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Jul. 22, 2005
Applicants:
Barbara Capecchi, Siena, IT;
Vega Masignani, Siena, IT;
Rino Rappuoli, Castelnuovo Berardenga, IT;
Maria Scarselli, Siena, IT;
Inventors:
Barbara Capecchi, Siena, IT;
Vega Masignani, Siena, IT;
Rino Rappuoli, Castelnuovo Berardenga, IT;
Maria Scarselli, Siena, IT;
Assignee:
Novartis AG, Basel, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A system for expressing antigenic polypeptides in oligomeric form fuses the antigenic polypeptide to an oligomerisation polypeptide such that the oligomerisation polypeptide can interact with other oligomerisation polypeptides and bring multiple copies of the antigenic polypeptide into close proximity in the form of an oligomer. Expressing the polypeptides in oligomeric form in this way can improve their immunogenicity compared to a monomeric form.