The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Mar. 20, 2006
Michael A. Caligiuri, Columbus, OH (US);
Aharon G. Freud, Columbus, OH (US);
Michael B. Becknell, Westerville, OH (US);
Michael A. Caligiuri, Columbus, OH (US);
Aharon G. Freud, Columbus, OH (US);
Michael B. Becknell, Westerville, OH (US);
The Ohio State University Research Foundation, Columbus, OH (US);
Abstract
The present invention provides isolated cells that are selectively enriched for hematopoietic progenitor cells that are precursors for natural killer (NK) cells. These cells are both CD34 and CD45RA positive and express C-integrin β, and are referred to as CD34CD45RAC-integrin β. The invention provides methods for isolating these cells, for inducing formation of CD56NK cells, and for treating diseases associated with immunodeficiency and cancer.