The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Jun. 18, 2001
Anthony E. Storey, Amersham, GB;
Georg Brauers, Amersham, GB;
Koichi Hanaoka, Sodegaura, JP;
Yoshihito Minosako, Sodegaura, JP;
Koichi Homma, Sodegaura, JP;
Yoshifumi Shirakami, Sodegaura, JP;
Anthony E. Storey, Amersham, GB;
Georg Brauers, Amersham, GB;
Koichi Hanaoka, Sodegaura, JP;
Yoshihito Minosako, Sodegaura, JP;
Koichi Homma, Sodegaura, JP;
Yoshifumi Shirakami, Sodegaura, JP;
GE Healthcare Limited, Buckinghamshire, GB;
Nihon Medi-Physics, Co., Ltd., Hyogo, JP;
Abstract
A stabilized radiopharmaceutical composition, a kit including same, and a method for making same, where the radiopharmaceutical is (i) susceptible to either reductive degradation or radiolysis and which includes a metal complex of a radionuclide with a ligand, (ii) a first stabilizer for the radiopharmaceutical which is an amino-substituted aromatic carboxylic acid or a salt, ester or amide thereof, and (iii) a second stabilizer for the radiopharmaceutical which is a diphosphonic acid or salt thereof. The first and second stabilizers are present in an amount effective to stabilize the radiopharmaceutical, and the radiopharmaceutical is not a metal complex of the diphosphonic acid.