The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2011
Filed:
Jun. 03, 2004
David W. Depaoli, Knoxville, TN (US);
Michael Z. HU, Knoxville, TN (US);
Saed Mirzadeh, Knoxville, TN (US);
John W. Clavier, Elizabethton, TN (US);
David W. DePaoli, Knoxville, TN (US);
Michael Z. Hu, Knoxville, TN (US);
Saed Mirzadeh, Knoxville, TN (US);
John W. Clavier, Elizabethton, TN (US);
UT-Battelle LLC, Oak Ridge, TN (US);
Abstract
Applicant's invention is a radionuclide generator resin material for radiochemical separation of daughter radionuclides, particularlyBi, from a solution of parental radionuclides, the resin material capable of providing clinical quantities ofBi of at least 20-mCi, wherein the resin material comprises a silica-based structure having at least one bifunctional ligand covalently attached to the surface of the silica-based structure. The bifunctional ligand comprises a chemical group having desirable surface functionality to enable the covalent attachment of the bifunctional ligand thereon the surface of the structure and the bifunctional ligand further comprises a second chemical group capable of binding and holding the parental radionuclides on the resin material while allowing the daughter radionuclides to elute off the resin material. The bifunctional ligand has a carbon chain with a limited number of carbons to maintain radiation stability of the resin material.