The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2011

Filed:

Sep. 18, 2009
Applicants:

Marc Nazare, Wiesbaden, DE;

Volkmar Wehner, Sandberg, DE;

David William Will, Kriftel, DE;

Hans Matter, Langenselbold, DE;

Inventors:

Marc Nazare, Wiesbaden, DE;

Volkmar Wehner, Sandberg, DE;

David William Will, Kriftel, DE;

Hans Matter, Langenselbold, DE;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/415 (2006.01); A61K 31/4245 (2006.01); C07D 413/02 (2006.01); C07D 419/02 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to a compound of formula I, in which R; R; R; R; R; Q; V, G and M have the meanings indicated below. The compound of formula I is a pharmacologically active compound. It exhibits a strong anti-thrombotic effect and is suitable, for example, for the therapy and prophylaxis of a cardio-vascular disorder like a thromboembolic disease or restenosis. It is a reversible inhibitor of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore is directed to a process for the preparation of the compound of formula I, and pharmaceutical preparation comprising it.


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