The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2011
Filed:
Dec. 29, 2006
Amjad Ali, Freehold, NJ (US);
Zhijian LU, Clinton, NJ (US);
Peter J. Sinclair, Scotch Plains, NJ (US);
Yi-heng Chen, Whippany, NJ (US);
Cameron J. Smith, Lawrenceville, NJ (US);
Hong LI, Edison, NJ (US);
Christopher F. Thompson, Clark, NJ (US);
Amjad Ali, Freehold, NJ (US);
Zhijian Lu, Clinton, NJ (US);
Peter J. Sinclair, Scotch Plains, NJ (US);
Yi-Heng Chen, Whippany, NJ (US);
Cameron J. Smith, Lawrenceville, NJ (US);
Hong Li, Edison, NJ (US);
Christopher F. Thompson, Clark, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B is a cyclic group other than phenyl, and B has a cyclic substituent at a position that is ortho to the position at which B is connected to the remainder of the structure of Formula (I). The 5-membered ring of Formula (I) has a second cyclic substituent in addition to B.