The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2011
Filed:
Dec. 27, 2005
Hiroyuki Ishiwata, Chiba, JP;
Mototsugu Kabeya, Tokyo, JP;
Toru Kanke, Tokyo, JP;
Kowa Company, Ltd., Nagoya-shi, JP;
Abstract
A compound, or a salt or solvate thereof having a structure of Ar—CO-AA-AA-AA-AA-NH—X—NRRis disclosed. Ar represents an optionally substituted phenyl group or an aromatic heterocyclic group; AArepresents a hydrophobic amino acid; AArepresents an unsubstituted amino acid containing 2 or more carbon atoms; AArepresents an unsubstituted amino acid containing 2 or more carbon atoms; AArepresents a hydrophobic amino acid; X represents a divalent saturated aliphatic hydrocarbon group having 2-6 carbon atoms; and Rand Rrepresent a saturated or unsubstituted aliphatic hydrocarbon group having 1-8 carbon atoms, or alternatively Rand Rmay form a ring together with an adjacent nitrogen atom. A pharmaceutical composition for prevention/treatment of diseases associated with PAR-2 is also disclosed. The pharmaceutical composition includes the above compound, a salt or a solvate thereof and a pharmaceutically acceptable carrier.