The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2011

Filed:

Feb. 22, 2007
Applicants:

Ashim K. Mitra, Overland Park, KS (US);

Soumyajit Majumdar, Oxford, MS (US);

Ritesh Jain, Kansas City, MO (US);

Yasser Nashed, Thousand Oaks, CA (US);

Inventors:

Ashim K. Mitra, Overland Park, KS (US);

Soumyajit Majumdar, Oxford, MS (US);

Ritesh Jain, Kansas City, MO (US);

Yasser Nashed, Thousand Oaks, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of treating a patient for a condition wherein the bioactive agent of choice is DRUG, wherein DRUG is a substrate that is effluxed by the P-gp transporter, is provided, the method comprising administering to the patient an effective amount of a compound of formula (I):DRUG-X—Y—Z—Z'—R  (I)wherein each X, Y, Z, and Z′ is independently Met, Val, Thr, Tyr, Trp, Ser, Ala, or Gly; R is H or an amino-protecting group; n is 1, and each n′, or n″ is independently 0 or 1; or a pharmaceutically acceptable salt thereof, with the proviso that DRUG is not acyclovir or ganciclovir and that DRUG is non-peptidyl.


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