The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2011
Filed:
Jun. 10, 2005
Soluble zcytor14, anti-zcytor14 antibodies and binding partners and methods of using in inflammation
Steven D. Levin, Seattle, WA (US);
Rolf E. Kuestner, Bothell, WA (US);
Zeren Gao, Redmond, WA (US);
Stephen R. Jaspers, Edmonds, WA (US);
Janine Bilsborough, Seattle, WA (US);
Steven D. Levin, Seattle, WA (US);
Rolf E. Kuestner, Bothell, WA (US);
Zeren Gao, Redmond, WA (US);
Stephen R. Jaspers, Edmonds, WA (US);
Janine Bilsborough, Seattle, WA (US);
ZymoGenetics, Inc., Seattle, WA (US);
Abstract
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. ZcytoR14 is a common receptor for IL-17A and IL-17F. The present invention includes soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners, as well as methods for antagonizing IL-17F, IL-17A or both IL-17A and IL-17F using such soluble receptors, antibodies and binding partners.