The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2011

Filed:

Jul. 07, 2005
Applicants:

Sergei Vladimirovich Benevolensky, Moscow, RU;

Alexei Nikolaevich Marchenko, Moscow, RU;

Dmitry Georgievich Kozlov, Moscow, RU;

Sergei Sergeevich Zatsepin, Moscow, RU;

Lyudmila Nikolaevna Shingarova, Moscow, RU;

Igor Vyacheslavovich Dudich, Moskovskaya Obl., RU;

Lidiya Nikolaevna Semenkova, Moskovskaya Obl., RU;

Dmitry Igorevich Dudich, Moskovskaya Obl., RU;

Eduard Borisovich Tatulov, Moscow, RU;

Elena Ivanovna Dudich, Moskovskaya Obl., RU;

Inventors:

Sergei Vladimirovich Benevolensky, Moscow, RU;

Alexei Nikolaevich Marchenko, Moscow, RU;

Dmitry Georgievich Kozlov, Moscow, RU;

Sergei Sergeevich Zatsepin, Moscow, RU;

Lyudmila Nikolaevna Shingarova, Moscow, RU;

Igor Vyacheslavovich Dudich, Moskovskaya Obl., RU;

Lidiya Nikolaevna Semenkova, Moskovskaya Obl., RU;

Dmitry Igorevich Dudich, Moskovskaya Obl., RU;

Eduard Borisovich Tatulov, Moscow, RU;

Elena Ivanovna Dudich, Moskovskaya Obl., RU;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C12N 1/16 (2006.01); C12N 1/19 (2006.01); C12N 5/00 (2006.01); C12N 15/12 (2006.01); C12N 15/81 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to the microbiological and medical industry, genetic engineering, biotechnology. Ayeast strain was obtained on the basis of constructing a recombinant plasmid DNA comprising a structural gene of a human alpha-fetoprotein (AFP) under the control of a regulatory promoter, providing the synthesis and production of AFP in a secreted soluble form, this AFP having activity identical or similar to the activity of a human AFP. The obtained recombinant AFP may be used as an active substance for the preparation of therapeutic agents for use in oncology, immunotherapy, cosmetology and also for the diagnosis of cancer and embryonic pathologies.


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