The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2011
Filed:
Oct. 04, 2005
Walter Stühmer, Göttingen, DE;
Hendrik Knötgen, Penzberg, DE;
David Gómez-varela, Del Mar, CA (US);
Luis A. Pardo, Göttingen, DE;
Mike Rothe, Krailling, DE;
Esther Zwick-wallasch, Gauting, DE;
Kerstin Dehne, München, DE;
Walter Stühmer, Göttingen, DE;
Hendrik Knötgen, Penzberg, DE;
David Gómez-Varela, Del Mar, CA (US);
Luis A. Pardo, Göttingen, DE;
Mike Rothe, Krailling, DE;
Esther Zwick-Wallasch, Gauting, DE;
Kerstin Dehne, München, DE;
Max-Planck-Gesellschaft zur Forderung der Wissen, Munich, DE;
Abstract
The present invention relates to a particularly advantageous antibody, antibody fragment or derivative thereof, which specifically binds to/interacts with at least one epitope of the extracellular or intracellular domain or the mammalian EAG1 ion channel and to nucleic acid molecules encoding these anti-EAG1 antibodies, antibody fragments or derivatives and to vectors comprising such nucleic acid molecules. The invention additionally relates to methods for the preparation of such anti-EAG1 antibodies, antibody fragments or derivatives thereof, pharmaceutical compositions comprising these antibodies, antibody fragments or derivatives, and methods of using the antibodies, antibody fragments or derivatives or the compositions for a variety of purposes, such as diagnosing disease, treating disease, assessing for the presence of EAG1-expressing cells, or blocking EAG1 function in cells.