The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2011
Filed:
Oct. 26, 2007
Francis J. Mcmahon, Bethesda, MD (US);
Gonzalo E. Laje, Potomac, MD (US);
Silvia Paddock, Solna, SE;
Husseini K. Manji, Cabin John, MD (US);
A. John Rush, Dallas, TX (US);
Francis J. McMahon, Bethesda, MD (US);
Gonzalo E. Laje, Potomac, MD (US);
Silvia Paddock, Solna, SE;
Husseini K. Manji, Cabin John, MD (US);
A. John Rush, Dallas, TX (US);
The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);
Board of Regents, the University of Texas System, Austin, IL (US);
Abstract
The invention provides a method of screening patients to identify those patients more likely to exhibit an increased risk of treatment-emergent suicidal ideation comprising: (a) obtaining a sample of genetic material from the patients, and (b) assaying the sample for the presence of a genotype in the patients which is associated with an increased risk of treatment-emergent suicidal ideation, wherein the genotype is characterized by a polymorphism in a gene selected from the group consisting of glutamine receptor, ionotropic, kainate 2 (GRIK2); glutamate receptor ionotropic AMPA 3 (GRIA3); and combinations thereof.