The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2011
Filed:
Jun. 27, 2007
Eric Dustin Agdeppa, Fairview, NJ (US);
Srabani Bhaumik, Niskayuna, NY (US);
June Klimash, Nikayuna, NY (US);
Jeannette Christine Depuy, Watervliet, NY (US);
Anton Beletskii, Niskayuna, NY (US);
Eric Dustin Agdeppa, Fairview, NJ (US);
Srabani Bhaumik, Niskayuna, NY (US);
June Klimash, Nikayuna, NY (US);
Jeannette Christine DePuy, Watervliet, NY (US);
Anton Beletskii, Niskayuna, NY (US);
General Electric Company, Niskayuna, NY (US);
Abstract
Provided herein are methods of monitoring inflammatory cell migration in a mammal. The methods include the steps of: providing a donor mammalian subject; introducing an inflammatory agent into the donor mammal to create a granuloma; isolating granuloma-derived nucleated cells from the granuloma of the donor mammalian subject; labeling the granuloma-derived nucleated cells with an optical agent; providing a recipient mammalian subject with inflamed tissue; introducing the granuloma-derived nucleated cells into a recipient mammalian subject at a site remote from site where the inflammatory agent was introduced; and imaging the recipient mammalian subject using an optical system. The methods may also include analysing the distribution of the labeled granuloma-derived cells in the recipient mammal.