The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2011

Filed:

Oct. 31, 2007
Applicants:

Sergey A. Selifonov, Los Altos, CA (US);

Willem P. C. Stemmer, Los Gatos, CA (US);

Claes Gustafsson, Belmont, CA (US);

Matthew Tobin, San Jose, CA (US);

Stephen Del Cardayre, Belmont, CA (US);

Phillip A. Patten, Menlo Park, CA (US);

Jeremy Minshull, Menlo Park, CA (US);

Lorraine J. Giver, Sunnyvale, CA (US);

Inventors:

Sergey A. Selifonov, Los Altos, CA (US);

Willem P. C. Stemmer, Los Gatos, CA (US);

Claes Gustafsson, Belmont, CA (US);

Matthew Tobin, San Jose, CA (US);

Stephen del Cardayre, Belmont, CA (US);

Phillip A. Patten, Menlo Park, CA (US);

Jeremy Minshull, Menlo Park, CA (US);

Lorraine J. Giver, Sunnyvale, CA (US);

Assignee:

Codexis Mayflower Holding, LLC, Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/48 (2006.01); G06G 7/58 (2006.01);
U.S. Cl.
CPC ...
Abstract

In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination. In certain embodiments, the methods involve inputting amino acid sequence character strings into a digital system and back-translating the amino acid character strings into a plurality of nucleic acid character strings. The nucleic acid character strings are then processed to define and select at least one recombinant nucleic acid for use in identifying one or more oligonucleotides for in vitro recombination.


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